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Article

PDE4D gene variants and haplotypes are associated with asthma and atopy in Brazilian children.

Immunobiology - 1 Sept 2023

Silva Hatilla Dos Santos, Teixeira Helena Mariana Pitangueira, Gomes Luciano Gama da Silva, Cruz Álvaro A, Alcantara-Neves Neuza Maria, Barreto Maurício, Figueiredo Camila Alexandrina, Costa Ryan Dos Santos

Abstract excerpt

PDE4D (Phosphodiesterase 4D) gene encodes a hydrolase of cyclic AMP. PDE4D genetic variants have been associated with asthma susceptibility. Therefore, this study aimed to investigate the association between PDE4D variants (and haplotypes) with asthma and atopy in a Brazilian population. The study comprised 1,246 unrelated participants from the SCAALA (Social Changes Asthma and Allergy in Latin America) program....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37549468
DOI: 10.1016/j.imbio.2023.152724

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