Article
Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children.
European journal of human genetics : EJHG - 1 Apr 2017
Marques Cintia Rodrigues, Costa Gustavo No, da Silva Thiago Magalhães, Oliveira Pablo, Cruz Alvaro A, Alcantara-Neves Neuza Maria, Fiaccone Rosemeire L, Horta Bernardo L, Hartwig Fernando Pires, Burchard Esteban G, Pino-Yanes Maria, Rodrigues Laura C, Lima-Costa Maria Fernanda, Pereira Alexandre C, Gouveia Mateus H, Sant Anna Hanaisa P, Tarazona-Santos Eduardo, Lima Barreto Maurício, Figueiredo Camila Alexandrina
Abstract excerpt
Several genome-wide association studies have been conducted to investigate the influence of genetic polymorphisms in the development of allergic diseases, but few of them have included the X chromosome. The aim of present study was to perform an X chromosome-wide association study (X-WAS) for asthma symptoms. The study included 1307 children of which 294 were asthma cases. DNA was genotyped using 2.5 HumanOmni...
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