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Article

Detection of MYD88 and CXCR4 mutations in cell-free DNA of patients with IgM monoclonal gammopathies.

Leukemia - 1 Dec 2018

Bagratuni Tina, Ntanasis-Stathopoulos Ioannis, Gavriatopoulou Maria, Mavrianou-Koutsoukou Nefeli, Liacos Christine, Patseas Dimitrios, Kanellias Nikolaos, Migkou Magdalini, Ziogas Dimitrios C, Eleutherakis-Papaiakovou Evangelos, Roussou Maria, Fotiou Despina, Terpos Evangelos, Kastritis Efstathios, Dimopoulos Meletios A

Abstract excerpt

Liquid biopsyis being integrated into cancer diagnostics with profound therapeutic implications. However, its role in Waldenström's Macroglobulinemia (WM) and IgM monoclonal gammopathies is still unclear. In this study, we evaluated the role of peripheral blood (PB) cell-free DNA (cfDNA) in characterizing the mutational status of MYD88 and CXCR4 of patients with IgM monoclonal gammopathies. Paired bone marrow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30026568
DOI: 10.1038/s41375-018-0197-7
PMCID: PMC6286389

Genes

CXCR4
MYD88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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