Article
Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research - 2 Dec 2024
Yan Yuting, Yu Ying, Xiong Wenjie, Wang Jun, Yao Yao, Jia Yujiao, Huang Yanshan, Li Yuxi, Wang Tingyu, Lyu Rui, Sun Hao, Wang Haoxu, Wang Qi, Liu Wei, An Gang, Sui Weiwei, Xu Yan, Huang Wenyang, Yu Zhen, Zou Dehui, Hao Mu, Xiao Zhijian, Wang Jianxiang, Qiu Lugui, Yi Shuhua
Abstract excerpt
PURPOSE: This study aims to explore the incidence and clinical features of MYD88 and CXCR4 mutations in patients with Waldenström macroglobulinemia (WM) and determine the optimal method for routine clinical practice. Additionally, we seek to evaluate the prognostic significance of these features across various therapeutic backgrounds [the cytotoxic group, the rituximab/bortezomib-based group, and the Bruton...
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