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Article

Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2018

Hirai Hiroyuki, Yang Bo, Garcia-Barrio Minerva T, Rom Oren, Ma Peter X, Zhang Jifeng, Chen Y Eugene

Abstract excerpt

Objective- To identify the transcription factors that could contribute to direct reprogramming of fibroblasts toward smooth muscle cell fate. Approach and Results- We screened various combinations of transcription factors, including Myocd (myocardin), Mef2C (myocyte enhancer factor 2C), Mef2B (myocyte enhancer factor 2B), Mkl1 (MKL [megakaryoblastic leukemia]/Myocd-like 1), Gata4 (GATA-binding protein 4), Gata5...

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Identifiers

PMID: 30026272
DOI: 10.1161/ATVBAHA.118.310870
PMCID: PMC6434534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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