Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal Myocytes

25 Jan 2011

Abstract excerpt

There is great interest in transdifferentiating cells from one lineage into those of another and in dedifferentiating mature cells back into a stem/progenitor cell state by deploying naturally occurring transcription factors (TFs). Often, however, steering cellular differentiation pathways in a predictable and efficient manner remains challenging. Here, we investigated the principle of combining domains from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Muscle Physiology and Disorders
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21266958
DOI: 10.1038/mt.2010.308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal MyocytesPMID 21266958Read ↗

Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle.Semantic proximity Read ↗

Dual-regulated myoD- and msx1-based interventions in C2C12-derived cells enable precise myogenic/osteogenic/adipogenic lineage control.Semantic proximity Read ↗

Myogenic Differentiation of Muscular Dystrophy-Specific Induced Pluripotent Stem Cells for Use in Drug DiscoverySemantic proximity Read ↗

Enhancement of Myogenic and Muscle Repair Capacities of Human Adipose–derived Stem Cells With Forced Expression of MyoDSemantic proximity Read ↗

Direct Reprogramming into Desired Cell Types by Defined FactorsSemantic proximity Read ↗

Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report.Semantic proximity Read ↗

Direct reprogramming of mouse fibroblasts into cardiac myocytes.Semantic proximity Read ↗

Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcomeSemantic proximity Read ↗

Designed Minibinders Rewire Receptor Signaling to Enable Functional Human Myogenic ReprogrammingSemantic proximity Read ↗

Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model.Semantic proximity Read ↗

Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell LineageSemantic proximity Read ↗

A Muscle Hybrid Promoter as a Novel Tool for Gene TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.