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Article

Reprogramming of human fibroblasts toward a cardiac fate.

Proceedings of the National Academy of Sciences of the United States of America - 2 Apr 2013

Nam Young-Jae, Song Kunhua, Luo Xiang, Daniel Edward, Lambeth Kaleb, West Katherine, Hill Joseph A, DiMaio J Michael, Baker Linda A, Bassel-Duby Rhonda, Olson Eric N

Abstract excerpt

Reprogramming of mouse fibroblasts toward a myocardial cell fate by forced expression of cardiac transcription factors or microRNAs has recently been demonstrated. The potential clinical applicability of these findings is based on the minimal regenerative potential of the adult human heart and the limited availability of human heart tissue. An initial but mandatory step toward clinical application of this...

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23487791
DOI: 10.1073/pnas.1301019110
PMCID: PMC3619357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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