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Transcription Factors – the Essence of Heart Regeneration:A Potential Novel Therapeutic Strategy

16 Feb 2022

Abstract excerpt

Myocardial cell injury and following sequelae are the primary reasons for death globally. Unfortunately, myocardiocytes in adults have limited regeneration capacity. Therefore, the generation of neo myocardiocytes from non-myocardial cells is a surrogate strategy. Transcription factors (TFs) can be recruited to achieve this tremendous goal. Transcriptomic analyses have suggested that GATA, Mef2c, and Tbx5 (GMT...

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Share to Cardiac Fibrosis and Remodeling
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PMID: 35170408
DOI: 10.2174/1566524022666220216123650

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