Article
Direct reprogramming of mouse fibroblasts into cardiac myocytes.
Journal of cardiovascular translational research - 1 Feb 2013
Inagawa Kohei, Ieda Masaki
Abstract excerpt
The potency of specific transcription factors as cell fate determinants was first demonstrated by the discovery of MyoD, a master gene for skeletal muscle transdifferentiation. More recently, the induction of pluripotency in somatic cells using a combination of stem cell-specific transcription factors has been reported. That elegant study altered the approach to regenerative medicine and inspired new strategies...
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