Article
Meta-Analysis of Transcriptome Regulation During Induction to Cardiac Myocyte Fate From Mouse and Human Fibroblasts.
Journal of cellular physiology - 1 Aug 2017
Rastegar-Pouyani Shima, Khazaei Niusha, Wee Ping, Yaqubi Moein, Mohammadnia Abdulshakour
Abstract excerpt
Ectopic expression of a defined set of transcription factors (TFs) can directly convert fibroblasts into a cardiac myocyte cell fate. Beside inefficiency in generating induced cardiomyocytes (iCMs), the molecular mechanisms that regulate this process remained to be well defined. The main purpose of this study was to provide better insight on the transcriptome regulation and to introduce a new strategy for...
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