Article
Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development.
PloS one - 1 Jan 2018
Alkaissi Hammoudi, Havarinasab Said, Nielsen Jesper Bo, Söderkvist Peter, Hultman Per
Abstract excerpt
Systemic autoimmune rheumatic disorders (SARD) represent important causes of morbidity and mortality in humans. The mechanisms triggering autoimmune responses are complex and involve a network of genetic factors. Mercury-induced autoimmunity (HgIA) in mice is an established model to study the mechanisms of the development of antinuclear antibodies (ANA), which is a hallmark in the diagnosis of SARD. A.SW mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
