Article
Nuclear Factor-kappaB in Autoimmunity: Man and Mouse.
Frontiers in immunology - 1 Jan 2018
Miraghazadeh Bahar, Cook Matthew C
Abstract excerpt
NF-κB (nuclear factor-kappa B) is a transcription complex crucial for host defense mediated by innate and adaptive immunity, where canonical NF-κB signaling, mediated by nuclear translocation of RelA, c-Rel, and p50, is important for immune cell activation, differentiation, and survival. Non-canonical signaling mediated by nuclear translocation of p52 and RelB contributes to lymphocyte maturation and survival and...
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