Article
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter.
Nature - 1 Jan 2000
Takahashi K, Vigneron M, Matthes H, Wildeman A, Zenke M, Chambon P
Abstract excerpt
The distance between the simian virus 40 early promoter elements has been altered by inserting either odd or even multiples of half a DNA turn. There are marked differences in the in vivo effects of these two types of insertions on initiation of transcription from this promoter.
Topics
- Base Sequence
- Chromosome Deletion
- DNA, Viral
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- Gene Expression Regulation
- Mutation
- Nucleic Acid Conformation
- Promoter Regions, Genetic
- Protein Binding
- Simian virus 40
- Transcription Factors
- Transcription, Genetic