Article
The Initiation of Simian Virus 40 DNA Replication<i>In Vitro</i>
1 Jan 1997
Abstract excerpt
DNA replication is a complicated process that is largely regulated during stages of initiation. The Siman Virus 40 in vitro replication system has served as an excellent model for studies of the initiation of DNA replication, and its regulation, in eukaryotes. Initiation of SV40 replication requires a single viral protein termed T-antigen, all other proteins are supplied by the host. The recent determination of...
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