Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses.

doi:10.1128/mcb.12.12.5386-5393.1992

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Article

Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses.

Molecular and cellular biology - 1 Dec 1992

Schek N, Cooke C, Alwine J C

Abstract excerpt

The polyadenylation signal for the late mRNAs of simian virus 40 is known to have sequence elements located both upstream and downstream of the AAUAAA which affect efficiency of utilization of the signal. The upstream efficiency element has been previously characterized by using deletion mutation...

Topics

Base Sequence
HeLa Cells
Humans
Molecular Sequence Data
Mutation
Poly A
RNA, Messenger
RNA, Viral
Regulatory Sequences, Nucleic Acid
Simian virus 40
Transcription, Genetic

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