Article
Duplications of a mutated simian virus 40 enhancer restore its activity.
Nature - 1 Jan 2000
Herr W, Gluzman Y
Abstract excerpt
Enhancers are cis-acting control elements which can stimulate at a distance the activity of a variety of eukaryotic promoters. First identified as a repeated 72 base pair (bp) sequence upstream of the simian virus 40 (SV40) early gene promoter, enhancers have since been shown to be associated with numerous other viral and cellular genes. Although there are no strong homologies between the sequences of different...
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