Duplications of a mutated simian virus 40 enhancer restore its activity.

doi:10.1038/313711a0

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Article

Duplications of a mutated simian virus 40 enhancer restore its activity.

Nature - 1 Jan 2000

Herr W, Gluzman Y

Abstract excerpt

Enhancers are cis-acting control elements which can stimulate at a distance the activity of a variety of eukaryotic promoters. First identified as a repeated 72 base pair (bp) sequence upstream of the simian virus 40 (SV40) early gene promoter, enhancers have since been shown to be associated wit...

Topics

DNA, Recombinant
Enhancer Elements, Genetic
Gene Expression Regulation
Genes, Regulator
Globins
Mutation
Phenotype
Simian virus 40

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