Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoter.

Journal of virology - 1 Feb 1995

Nahreini P, Mathews M B

Abstract excerpt

Positive and negative effects of DNA replication on gene transcription have been documented in a variety of systems. We examined the effects of the simian virus 40 (SV40) origin of replication on transcription from the human immunodeficiency virus type 1 (HIV-1) promoter, using a transient expression assay in COS-1 cells. The basal activity and Tat transactivation of the HIV promoter were greatly stimulated by...

Topics

Cell Line
DNA Replication
Gene Expression
HIV Long Terminal Repeat
HIV-1
Mutation
Promoter Regions, Genetic
Simian virus 40
Transcription, Genetic
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 7815509
DOI: 10.1128/JVI.69.2.1296-1301.1995
PMCID: PMC188708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7815509-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoter.PMID 7815509Read ↗

The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.Semantic proximity Read ↗

Transcriptional activation by simian virus 40 large T antigen: requirements for simple promoter structures containing either TATA or initiator elements with variable upstream factor binding sitesSemantic proximity Read ↗

Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages.Semantic proximity Read ↗

Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.Semantic proximity Read ↗

HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start siteSemantic proximity Read ↗

Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts.Semantic proximity Read ↗

The Initiation of Simian Virus 40 DNA Replication<i>In Vitro</i>Semantic proximity Read ↗

The Human Immunodeficiency Virus Long Terminal Repeat Includes a Specialised Initiator Element which is Required for Tat-responsive TranscriptionSemantic proximity Read ↗

Role of Host Factors on the Regulation of Tat-Mediated HIV-1 TranscriptionSemantic proximity Read ↗

Repression of simian virus 40 early transcription by viral DNA replication in human 293 cells.Semantic proximity Read ↗

Regulation of cellular gene expression and function by the human immunodeficiency virus type 1 tat proteinSemantic proximity Read ↗

Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.