Article
Domains of the rat rDNA promoter must be aligned stereospecifically.
Molecular and cellular biology - 1 Mar 1992
Xie W Q, Rothblum L I
Abstract excerpt
Efficient transcription from the rat rDNA promoter results from an undefined interaction between the core (CPE) and upstream (UPE) promoter elements or the protein complexes which form on them. These interactions were demonstrated by the behavior of promoters that contained either linker-scanning or deletion mutations of the UPE in combination with point mutations of the CPE (bidomain mutants). In vivo...
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