Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic Cigarette Smoke Exposure Subdues PP2A Activity by Enhancing Expression of the Oncogene CIP2A

16 Jul 2018

Abstract excerpt

Phosphatase activity of the major serine threonine phosphatase, protein phosphatase 2A (PP2A), is blunted in the airways of individuals with chronic obstructive pulmonary disease (COPD), which results in heightened inflammation and proteolytic responses. The objective of this study was to investigate how PP2A activity is modulated in COPD airways. PP2A activity and endogenous inhibitors of PP2A were investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Neonatal Respiratory Health Research
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30011381
DOI: 10.1165/rcmb.2018-0173oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic Cigarette Smoke Exposure Subdues PP2A Activity by Enhancing Expression of the Oncogene CIP2APMID 30011381Read ↗

Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer.Semantic proximity Read ↗

Suppression of PP2A-B56α Drives EMT in EGFR Mutant Non-Small Cell Lung CancerSemantic proximity Read ↗

PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE ExposureSemantic proximity Read ↗

All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Semantic proximity Read ↗

Role and regulation of MKP-1 in airway inflammationSemantic proximity Read ↗

FUNCTIONAL DIVERSITY OF MAMMALIAN TYPE 2C PROTEIN PHOSPHATASE ISOFORMS: NEW TALES FROM AN OLD FAMILYSemantic proximity Read ↗

A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non-small cell lung cancer.Semantic proximity Read ↗

Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and CancerSemantic proximity Read ↗

Functional importance of PP2A regulatory subunit loss in breast cancer.Semantic proximity Read ↗

PRKN-regulated mitophagy and cellular senescence during COPD pathogenesisSemantic proximity Read ↗

Cancerous Inhibitor of Protein Phosphatase 2A, an Emerging Human Oncoprotein and a Potential Cancer Therapy TargetSemantic proximity Read ↗

A transcriptomics-guided drug target discovery strategy identifies novel receptor ligands for lung regenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.