Article

Suppression of PP2A-B56α Drives EMT in EGFR Mutant Non-Small Cell Lung Cancer

2025-07-18

Abstract excerpt

<h4>ABSTRACT</h4> Lung cancer is the leading cause of cancer-related deaths in the United States and ∼50% of these patients present with metastatic disease at diagnosis. Epithelial-to-Mesenchymal Transition (EMT) is an important initiating step in the metastatic cascade that allows cells to acquire the migratory and invasive phenotypes necessary for dissemination. The transcriptional reprogramming that takes plac...

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Literature Corpus work: f0d3549a-3202-574a-b1a1-bbe45ad85808
DOI: 10.1101/2025.07.14.664751

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