Article

A transcriptomics-guided drug target discovery strategy identifies novel receptor ligands for lung regeneration

2021-05-18

Abstract excerpt

Currently, there is no pharmacological treatment targeting defective tissue repair in chronic disease. Here we utilized a transcriptomics-guided drug target discovery strategy using gene signatures of smoking-associated chronic obstructive pulmonary disease (COPD) and from mice chronically exposed to cigarette smoke, identifying druggable targets expressed in alveolar epithelial progenitors of which we screened th...

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Literature Corpus work: dc82bc8a-5556-5ba0-a2e1-91bc24f746d0
DOI: 10.1101/2021.05.18.444655

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