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Article

Role and regulation of MKP-1 in airway inflammation

10 Aug 2017

Abstract excerpt

Mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1) is a protein with anti-inflammatory properties and the archetypal member of the dual-specificity phosphatases (DUSPs) family that have emerged over the past decade as playing an instrumental role in the regulation of airway inflammation. Not only does MKP-1 serve a critical role as a negative feedback effector, controlling the extent and duration of...

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PMID: 28797290
DOI: 10.1186/s12931-017-0637-3

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