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Article

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping.

Journal of visualized experiments : JoVE - 29 Jun 2018

Kosuta Ceres, Daniel Kate, Johnstone Devon L, Mongeon Kevin, Ban Kevin, LeBlanc Sophie, MacLeod Stuart, Et-Tahiry Karim, Ekker Marc, MacKenzie Alex, Pena Izabella

Abstract excerpt

Zebrafish (Danio rerio) possess orthologues for 84% of the genes known to be associated with human diseases. In addition, these animals have a short generation time, are easy to handle, display a high reproductive rate, low cost, and are easily amenable to genetic manipulations by microinjection of DNA in embryos. Recent advances in gene editing tools are enabling precise introduction of mutations and transgenes...

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Identifiers

PMID: 30010654
DOI: 10.3791/58024
PMCID: PMC6102016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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