Article
Automated multi-sample DNA extraction for genotyping live Xenopus embryos.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2023
Alles Narmadha, Guille Matthew, Górecki Dariusz C
Abstract excerpt
BACKGROUND: Xenopus frogs are used extensively for modeling genetic diseases owing to characteristics such as the abundance of eggs combined with their large size, allowing easy manipulation, and rapid external embryo development enabling the examination of cellular and phenotypic alterations throughout embryogenesis. However, genotyping of mutant animals is currently done either as part of a large group,...
Topics
- Animals
- Xenopus
- Xenopus laevis
- Zebrafish
- Genotype
- Xenopus Proteins
- Embryo, Nonmammalian