Article
Genetic variation in the zebrafish.
Genome research - 1 Apr 2006
Guryev Victor, Koudijs Marco J, Berezikov Eugene, Johnson Stephen L, Plasterk Ronald H A, van Eeden Fredericus J M, Cuppen Edwin
Abstract excerpt
Although zebrafish was introduced as a laboratory model organism several decades ago and now serves as a primary model for developmental biology, there is only limited data on its genetic variation. An establishment of a dense polymorphism map becomes a requirement for effective linkage analysis and cloning approaches in zebrafish. By comparing ESTs to whole-genome shotgun data, we predicted >50,000 high-quality...
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