A pooling strategy to effectively use genotype data in quantitative traits genome-wide association studies.

Abstract excerpt

The goal of quantitative traits genome-wide association studies is to identify associations between a phenotypic variable, such as a vitamin level and genetic variants, often single-nucleotide polymorphisms. When funding limits the number of assays that can be performed to measure the level of the phenotypic variable, a subgroup of subjects is often randomly selected from the genotype database and the level of...

Topics

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• Data Interpretation, Statistical
• Genome-Wide Association Study
• Genotype
• Models, Statistical
• Polymorphism, Single Nucleotide