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Article

Bayesian method for gene detection and mapping, using a case and control design and DNA pooling.

Biostatistics (Oxford, England) - 1 Jul 2007

Johnson Toby

Abstract excerpt

Association mapping studies aim to determine the genetic basis of a trait. A common experimental design uses a sample of unrelated individuals classified into 2 groups, for example cases and controls. If the trait has a complex genetic basis, consisting of many quantitative trait loci (QTLs), each group needs to be large. Each group must be genotyped at marker loci covering the region of interest; for dense...

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PMID: 16984977
DOI: 10.1093/biostatistics/kxl028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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