Evolutionary Distance Predicts Recurrence After Liver Transplantation in Multifocal Hepatocellular Carcinoma.

doi:10.1097/TP.0000000000002356

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Article

Evolutionary Distance Predicts Recurrence After Liver Transplantation in Multifocal Hepatocellular Carcinoma.

Transplantation - 1 Oct 2018

Heits Nils, Brosch Mario, Herrmann Alexander, Behrens Robin, Röcken Christoph, Schrem Harald, Kaltenborn Alexander, Klempnauer Jürgen, Kreipe Hans-Heinrich, Reichert Benedikt, Lenschow Christina, Wilms Christian, Vogel Thomas, Wolters Heiner, Wardelmann Eva, Seehofer Daniel, Buch Stephan, Zeissig Sebastian, Pannach Sven, Raschzok Nathanael, Dietel Manfred, von Schoenfels Witigo, Hinz Sebastian, Teufel Andreas, Evert Matthias, Franke Andre, Becker Thomas, Braun Felix, Hampe Jochen, Schafmayer Clemens

Abstract excerpt

BACKGROUND: Liver transplantation (LTx) is a potentially curative treatment option for hepatocellular carcinoma (HCC) in cirrhosis. However, patients, where HCC is already a systemic disease, LTx may be individually harmful and has a negative impact on donor organ usage. Thus, there is a need for improved selection criteria beyond nodule morphology to select patients with a favorable outcome for LTx in multifocal...

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PMID: 29994984
DOI: 10.1097/TP.0000000000002356
PMCID: PMC7598094

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