Article
Genetic diversity of hepatitis C virus predicts recurrent disease after liver transplantation.
Virology - 5 Jul 2010
Li Hui, Sullivan Daniel G, Feuerborn Nathan, McArdle Susan, Bekele Kirubeal, Pal Sampa, Yeh Matthew, Carithers Robert L, Perkins James D, Gretch David R
Abstract excerpt
Approximately 20% of patients receiving liver transplants for end-stage hepatitis C rapidly develop severe allograph fibrosis within the first 24 months after transplant. Hepatitis C virus (HCV) variants were studied in 56 genotype-1-infected subjects with end-stage hepatitis C disease at the time before and 12 months after liver transplant, and post-transplant outcome was followed with serial liver biopsies. In...
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