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Article

Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2018

Palsgrove Doreen N, Brosnan-Cashman Jacqueline A, Giannini Caterina, Raghunathan Aditya, Jentoft Mark, Bettegowda Chetan, Gokden Murat, Lin Doris, Yuan Ming, Lin Ming-Tseh, Heaphy Christopher M, Rodriguez Fausto J

Abstract excerpt

Neurofibromatosis type-1 is a familial genetic syndrome associated with a predisposition to develop peripheral and central nervous system neoplasms. We have previously reported on a subset of gliomas developing in these patients with morphologic features resembling subependymal giant cell astrocytoma, but the molecular features of these tumors remain undefined. A total of 14 tumors were studied and all available...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29973652
DOI: 10.1038/s41379-018-0103-x
PMCID: PMC6269209

Genes

ATRX
BRAF
DAXX
FANCD2
FANCF
FANCG
IDH1
IDH2
PTEN
RECQL4
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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