Article
Granular cell astrocytoma: an aggressive IDH-wildtype diffuse glioma with molecular genetic features of primary glioblastoma.
Brain pathology (Zurich, Switzerland) - 1 Mar 2019
Vizcaino M Adelita, Palsgrove Doreen N, Yuan Ming, Giannini Caterina, Cabrera-Aldana Eibar Ernesto, Pallavajjala Aparna, Burger Peter C, Rodriguez Fausto J
Abstract excerpt
Granular cell astrocytoma (GCA) is a rare adult infiltrating glioma subtype. We studied a series of 39 GCAs. Median age of presentation was 57.8 years and most cases developed in the frontal or temporal lobes. Tumors included grade II (n = 14), grade III (n = 11), and grade IV (n = 14) by WHO criteria. Granular cell morphology was diffuse in 31 (79%) cases and partial in eight (21%). Immunohistochemistry showed...
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