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Article

Associations between Single Nucleotide Polymorphisms in the Mitochondrial DNA D-Loop Region and Outcome of Gastroenteropancreatic Neuroendocrine Neoplasm.

Annals of clinical and laboratory science - 1 May 2018

Er Li-Mian, Li Yong, Er Li, Wu MingLi, Zheng Xiu-Li, Guo Zhan-Jun, Yuan Hu-Fang

Abstract excerpt

Accumulation of single-nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) may be associated with cancer risk and disease outcome. We evaluated the predictive value of these SNPs for GEP-NEN outcome. Three SNP sites of nucleotides 16257C/A, 150C/T and 151C/Tdel were identified for statistically significant prediction of postoperative survival in GEP-NEN by univariate...

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PMID: 29970437

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