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Article

Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients.

BMC cancer - 3 Jul 2018

Real Sumayya Abdul Sattar, Parveen Farah, Rehman Asad Ur, Khan Mohammad Aasif, Deo Sankaravamasam Venkata Suryanarayan, Shukla Nootan Kumar, Husain Syed Akhtar

Abstract excerpt

BACKGROUND: YAP, a potent oncogene and major downstream effector of the mammalian Hippo tumor suppressor pathway can act as either oncogene or tumor suppressor gene based on the type of tissue involved. Despite various studies, the role and mechanism through which YAP mediates its tumor suppressor or oncogenic effects are not yet fully understood. Therefore in the present study we aimed to investigate YAP at DNA,...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29970036
DOI: 10.1186/s12885-018-4627-8
PMCID: PMC6031145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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