Article
The association between the expression of nuclear Yes-associated protein 1 (YAP1) and p53 protein expression profile in breast cancer patients.
PloS one - 1 Jan 2021
Cha Yoon Jin, Kim Dooreh, Bae Soong June, Ahn Sung Gwe, Jeong Joon, Cho Min Kyung, Paik Pill Sun, Yoo Tae-Kyung, Park Woo-Chan, Yoon Chang Ik
Abstract excerpt
BACKGROUND: Yes-associated protein 1 (YAP1) is a key effector molecule regulated by the Hippo pathway and described as a poor prognostic factor in breast cancer. Tumor protein 53 (TP53) mutation is well known as a biomarker related to poor survival outcomes. So far clinical characteristics and survival outcome according to YAP1 and TP53 mutation have been poorly identified in breast cancer. PATIENTS AND METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.