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Article

Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 May 2012

Wang Xiaodan, Su Lili, Ou Qishui

Abstract excerpt

Yes-associated protein (YAP) is inactivated by the tumour suppressing Hippo pathway. The YAP gene is amplified in human liver cancer, and promotes tumour growth. However, there are contrasting reports about its function in breast cancer. Studies have demonstrated both oncogenic or tumour suppressor functions. Our study aims to clarify the role of YAP in breast cancer. We investigated the expression of YAP in 69...

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Identifiers

PMID: 22056638
DOI: 10.1016/j.ejca.2011.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer.PMID 22056638Read ↗

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The association between the expression of nuclear Yes-associated protein 1 (YAP1) and p53 protein expression profile in breast cancer patients.Semantic proximity Read ↗

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Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients.Semantic proximity Read ↗

Targeting YAP and Hippo signaling pathway in liver cancerSemantic proximity Read ↗

Yes-associated protein plays oncogenic roles in human sporadic colorectal adenomas.Semantic proximity Read ↗

YAP and β-catenin co-operate to drive oncogenesis in basal breast cancerSemantic proximity Read ↗

Role of YAP-1 in Thyroid Tumor Progression and Outcome.Semantic proximity Read ↗

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