Variants in BANK1 are associated with lupus nephritis of European ancestry.

doi:10.1038/s41435-021-00142-8

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Article

Variants in BANK1 are associated with lupus nephritis of European ancestry.

Genes and immunity - 1 Jul 2021

Bolin Karin, Imgenberg-Kreuz Juliana, Leonard Dag, Sandling Johanna K, Alexsson Andrei, Pucholt Pascal, Haarhaus Malena Loberg, Almlöf Jonas Carlsson, Nititham Joanne, Jönsen Andreas, Sjöwall Christopher, Bengtsson Anders A, Rantapää-Dahlqvist Solbritt, Svenungsson Elisabet, Gunnarsson Iva, Syvänen Ann-Christine, Lerang Karoline, Troldborg Anne, Voss Anne, Molberg Øyvind, Jacobsen Søren, Criswell Lindsey, Rönnblom Lars, Nordmark Gunnel

Abstract excerpt

The genetic background of lupus nephritis (LN) has not been completely elucidated. We performed a case-only study of 2886 SLE patients, including 947 (33%) with LN. Renal biopsies were available from 396 patients. The discovery cohort (Sweden, n = 1091) and replication cohort 1 (US, n = 962) were genotyped on the Immunochip and replication cohort 2 (Denmark/Norway, n = 833) on a custom array. Patients with LN,...

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PMID: 34127828
DOI: 10.1038/s41435-021-00142-8
PMCID: PMC8277572

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