Article
Polymorphisms of TNF-α -308 G/A and IL-8 -251 T/A Genes Associated with Urothelial Carcinoma: A Case-Control Study.
BioMed research international - 1 Jan 2018
Wu Chia-Chang, Huang Yung-Kai, Huang Chao-Yuan, Shiue Horng-Sheng, Pu Yeong-Shiau, Su Chien-Tien, Lin Ying-Chin, Hsueh Yu-Mei
Abstract excerpt
Cigarette smoking and exposure to environmental tobacco smoke are well-known risk factors for urothelial carcinoma (UC). We conducted a hospital-based case-control study involving 287 UC cases and 574 cancer-free controls to investigate the joint effects of cigarette smoking and polymorphisms of inflammatory genes on UC risk. Tumor necrosis factor alpha (TNF-α) -308 G/A and interleukin-8 (IL-8) -251 T/A...
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