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Article

The polymorphism interleukin-8 -251A/T is associated with a significantly increased risk of cancers from a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014

Wang Ziliang, Liu Yang, Yang Lina, Yin Sheng, Zang Rongyu, Yang Gong

Abstract excerpt

Emerging evidences show that interleukin-8 (IL-8) has important regulatory functions in tumorigenesis. IL-8 -251A/T is a single nucleotide polymorphism in the promoter region of the IL-8 gene and affects IL-8 production. Analysis of previous studies on the association of -251A/T polymorphism with different cancer types remained to be illustrated. To further assess the effect of -251A/T polymorphism on cancer...

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PMID: 24760271
DOI: 10.1007/s13277-014-1881-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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