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Article

IL-8 -251A/T polymorphism is associated with decreased cancer risk among population-based studies: evidence from a meta-analysis.

European journal of cancer (Oxford, England : 1990) - 1 May 2010

Gao Lin-Bo, Pan Xin-Min, Jia Jing, Liang Wei-Bo, Rao Li, Xue Hui, Zhu Yi, Li Shi-Liu, Lv Mei-Li, Deng Wei, Chen Tian-Yi, Wei Yong-Gang, Zhang Lin

Abstract excerpt

Growing evidence suggests that interleukin-8 (IL-8) play pivotal roles in the pathogenesis of cancer through the modulation of tumour immune response or enhanced angiogenesis. A single nucleotide polymorphism, -251A/T, has been identified in the promoter region of the IL-8 gene and has been shown to influence its production. Results from previous studies on the association of -251A/T polymorphism with different...

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PMID: 20400292
DOI: 10.1016/j.ejca.2010.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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