Article
Genetic polymorphism of tumor necrosis factor alpha (TNF-α) and tumor necrosis factor beta (TNF-β) genes and risk of oral pre-cancer and cancer in North Indian population.
Oral and maxillofacial surgery - 1 Mar 2022
Gupta Shalini, Nigam Kumud, Srivastav Ratnesh Kumar, Ahmad Md Kaleem, Mahdi Abbas Ali, Sanyal Somali
Abstract excerpt
OBJECTIVE: There are inconclusive data connecting single-nucleotide polymorphisms (SNPs) of TNF-α (rs361525) and TNF-β (rs909253) to potential malignant oral disorder (PMOD) such as lichen planus and oral fibrosis. Here, we have investigated the risk of oral squamous cell carcinoma as well as oral pre-cancerous lesions in North Indian population with the polymorphism of the TNFα/ β genes. MATERIAL AND METHODS: A...
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