Tumor necrosis factor α -308 G>A polymorphisms and cervical cancer risk: a meta-analysis.

doi:10.1097/IGC.0b013e3182375aed

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Article

Tumor necrosis factor α -308 G>A polymorphisms and cervical cancer risk: a meta-analysis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Feb 2012

Ding Bo, Fu Shilong, Wang Meilin, Yue Cong, Wang Wei, Zhou Delan, Zhang Zhengdong, Han Suping

Abstract excerpt

OBJECTIVE: Tumor necrosis factor α (TNF-α), secreted mainly by activated macrophages, is recently involved in fighting against tumorigenesis. Tumor necrosis factor α -308 G>A, the common polymorphism in the promoter of TNF-α, has been implicated to alter the risk of cervical cancer, yet the results of relative studies are inconclusive or controversial. To derive a more precise estimation of the relationship, we...

Topics

Ethnicity
Female
Genetic Predisposition to Disease
Humans
Odds Ratio
Polymorphism, Single Nucleotide
Risk Factors
Tumor Necrosis Factor-alpha
Uterine Cervical Neoplasms

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Open in PubMed

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PMID: 22146770
DOI: 10.1097/IGC.0b013e3182375aed

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