Article
Polymorphism of inflammatory genes and arsenic methylation capacity are associated with urothelial carcinoma.
Toxicology and applied pharmacology - 1 Oct 2013
Wu Chia-Chang, Huang Yung-Kai, Chung Chi-Jung, Huang Chao-Yuan, Pu Yeong-Shiau, Shiue Horng-Sheng, Lai Li-An, Lin Ying-Chin, Su Chien-Tien, Hsueh Yu-Mei
Abstract excerpt
Chronic exposure to arsenic can generate reactive oxidative species, which can induce certain proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8). TNF-α, IL-6 and IL-8 have been shown to be involved in the development and progressio...
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