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Article

Clonal Structures of Regionally Synchronous Gastric Adenomas and Carcinomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2018

Jung Seung-Hyun, Kim Shin Young, An Chang Hyeok, Lee Sung Hak, Jung Eun Sun, Park Hyeon-Chun, Kim Min Sung, Chung Yeun-Jun, Lee Sug Hyung

Abstract excerpt

Purpose: Gastric adenoma (GA) is a premalignant lesion that precedes intestinal-type gastric carcinoma (GC). However, genetic progression mechanisms from GA to GC have not been clarified.Experimental Design: We performed whole-exome sequencing-based mutational analyses for 15 synchronous pairs of attached GAs and GCs.Results: There was no significant difference in the number of driver mutations or copy-number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29945994
DOI: 10.1158/1078-0432.CCR-18-0345

Genes

RPL22
APC
FAT1
GLI3
PREX2
RNF43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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