Article
Molecular characteristics of synchronous multiple gastric cancer.
Theranostics - 1 Jan 2020
Wang Anqiang, Li Zhongwu, Wang Meng, Jia Shuqin, Chen Jiahu, Ji Ke, Ji Xin, Zong Xianglong, Wu Xiaojiang, Zhang Ji, Li Ziyu, Zhang Lianhai, Hu Ying, Bu Zhaode, Zheng Qi, Ji Jiafu
Abstract excerpt
Rationale: Multiple gastric cancer (MGC) is characterized by the presence of more than two different tumors in the stomach. However, the clonal relationship and carcinogenesis of MGC remain unclear. We investigated the clonal relationship and role of germline mutations in the carcinogenesis of MGC. Methods: We gathered 16 multiple gastric cancer patients. Thirty-three tumor samples and sixteen normal gastric...
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