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Article

Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine

2020-05-07

Abstract excerpt

<h4>Background</h4> Small intestine neuroendocrine tumor (SI-NET), the most common cancer of the small bowel, often displays a curious multifocal phenotype with several intestinal tumors centered around a regional lymph node metastasis. Although SI-NET patients often present with metastatic disease at the time of diagnosis, there is an unusual absence of somatic driver mutations explaining tumor initiation and me...

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Literature Corpus work
7233fdd9-e187-55f4-b775-b4fb70f21070
DOI
10.1101/2020.05.06.080499
Open publication

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Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestineDOI 10.1101/2020.05.06.080499
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