Article
Elevated Numbers of HIV-Specific Poly-Functional CD8+ T Cells With Stem Cell-Like and Follicular Homing Phenotypes in HIV-Exposed Seronegative Individuals.
Frontiers in immunology - 1 Jan 2021
Munusamy Ponnan Sivasankaran, Thiruvengadam Kannan, Kathirvel Sujitha, Shankar Janani, Rajaraman Akshaya, Mathaiyan Manikannan, Dinesha Thongadi Ramesh, Poongulali Selvamuthu, Saravanan Shanmugam, Murugavel Kailapuri Gangatharan, Swaminathan Soumya, Tripathy Srikanth Prasad, Neogi Ujjwal, Velu Vijayakumar, Hanna Luke Elizabeth
Abstract excerpt
HIV-specific CD8+ T cells are known to play a key role in viral control during acute and chronic HIV infection. Although many studies have demonstrated the importance of HIV-specific CD8+ T cells in viral control, its correlation with protection against HIV infection remains incompletely understood. To better understand the nature of the immune response that contributes to the early control of HIV infection, we...
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