Article
Pleiotropic effects of n-6 and n-3 fatty acid-related genetic variants on circulating hemostatic variables.
Thrombosis research - 1 Aug 2018
Weng Lu-Chen, Guan Weihua, Steffen Lyn M, Pankow James S, Pankratz Nathan, Chen Ming-Huei, Cushman Mary, Basu Saonli, Folsom Aaron R, Tang Weihong
Abstract excerpt
INTRODUCTION: Data from epidemiological studies and clinical trials suggest an influence of dietary and circulating polyunsaturated fatty acids (PUFAs) on the hemostasis profile. Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) related to plasma PUFAs levels. We aimed to investigate whether the SNPs related to plasma PUFAs levels were also associated with plasma levels...
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