Article
Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study.
Journal of thrombosis and haemostasis : JTH - 1 Feb 2011
Zakai N A, Lange L, Longstreth W T, O'Meara E S, Kelley J L, Fornage M, Nikerson D, Cushman M, Reiner A P
Abstract excerpt
BACKGROUND: Thrombosis and inflammation are critical in stroke etiology, but associations of coagulation and inflammation gene variants with stroke, and particularly factor VII levels, are inconclusive. OBJECTIVES: To test the associations between 736 single-nucleotide polymorphisms (SNPs) between tagging haplotype patterns of 130 coagulation and inflammation genes, and stroke events, in the 5888 participants...
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