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Article

RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification.

Nucleic acids research - 27 Jul 2018

White Martin A, Azeroglu Benura, Lopez-Vernaza Manuel A, Hasan A M Mahedi, Leach David R F

Abstract excerpt

DNA double-strand break (DSB) repair is critical for cell survival. A diverse range of organisms from bacteria to humans rely on homologous recombination for accurate DSB repair. This requires both coordinate action of the two ends of a DSB and stringent control of the resultant DNA replication to prevent unwarranted DNA amplification and aneuploidy. In Escherichia coli, RecBCD enzyme is responsible for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29901759
DOI: 10.1093/nar/gky463
PMCID: PMC6061781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification.PMID 29901759Read ↗

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Recombinational repair of chromosomal DNA double-strand breaks generated by a restriction endonuclease.Semantic proximity Read ↗

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