Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RecO and RecR are necessary for RecA loading in response to DNA damage and replication fork stress.

Journal of bacteriology - 1 Aug 2014

Lenhart Justin S, Brandes Eileen R, Schroeder Jeremy W, Sorenson Roderick J, Showalter Hollis D, Simmons Lyle A

Abstract excerpt

RecA is central to maintaining genome integrity in bacterial cells. Despite the near-ubiquitous conservation of RecA in eubacteria, the pathways that facilitate RecA loading and repair center assembly have remained poorly understood in Bacillus subtilis. Here, we show that RecA rapidly colocalizes with the DNA polymerase complex (replisome) immediately following DNA damage or damage-independent replication fork...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus subtilis
Share to DNA Damage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to DNA Replication

Share to DNA, Single-Stranded

Share to Green Fluorescent Proteins

Share to Rec A Recombinases

Share to Uracil

Source

Open in PubMed Open full text

Identifiers

PMID: 24891441
DOI: 10.1128/JB.01494-14
PMCID: PMC4135682

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RecO and RecR are necessary for RecA loading in response to DNA damage and replication fork stress.PMID 24891441Read ↗

RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coli.Semantic proximity Read ↗

Bacillus subtilis RecA and its accessory factors, RecF, RecO, RecR and RecX, are required for spore resistance to DNA double-strand break.Semantic proximity Read ↗

RecA Is Required for the Assembly of RecN into DNA Repair Complexes on the Nucleoid.Semantic proximity Read ↗

Dynamic formation of RecA filaments at DNA double strand break repair centers in live cells.Semantic proximity Read ↗

The RecU Holliday junction resolvase acts at early stages of homologous recombination.Semantic proximity Read ↗

Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli.Semantic proximity Read ↗

Visualization of DNA double-strand break repair in live bacteria reveals dynamic recruitment of Bacillus subtilis RecF, RecO and RecN proteins to distinct sites on the nucleoids.Semantic proximity Read ↗

RecFOR function is required for DNA repair and recombination in a RecA loading-deficient recB mutant of Escherichia coli.Semantic proximity Read ↗

RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination.Semantic proximity Read ↗

RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis.Semantic proximity Read ↗

recF-dependent recombination as a SOS function.Semantic proximity Read ↗

Modulation of DNA damage tolerance in Escherichia coli recG and ruv strains by mutations affecting PriB, the ribosome and RNA polymerase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.